The Red Sox are bracing for some serious lineup and roster changes following a major blow to their infield.

Red Sox third baseman Alex Bregman could be nearing a trip to the injured list after leaving Friday’s game with right quadriceps tightness, manager Alex Cora said. “He’s getting an MRI. He’s sore,” Cora said at Fenway Park on Saturday morning before Boston was set to face the Baltimore Orioles in the first game of a split doubleheader.

The Red Sox are down two of their mainstay veteran infielders and a third is struggling badly, so rookies are taking centerstage.

So Marcelo Mayer’s debut didn’t quite the way he would have liked, going 0-4 with three strikeouts. But it was a memorable day nonetheless, featuring a standing ovation, a new position, and a scramble to find car keys he’d lost several weeks before. (Alex Speier, Boston Globe)

Boston Red Sox third baseman Alex Bregman will be out awhile with what manager Alex Cora called a significant right quad strain. The big free agent addition for the Red Sox left their game Friday

Trevor Rogers delivered a strong start in his season debut and the Orioles’ offense did just enough to salvage a doubleheader split.