本研究针对结构变异检测的技术瓶颈，创新性地比较了纳米孔测序（Nanopore Sequencing）与杂交SNP微阵列（hybrid-SNP microarray）在人类基因组拷贝数变异（CNV）检测中的性能。研究人员通过对两种白血病细胞系（EOL-1和697）的低深度测序（11-13X）分析，发现纳米孔测序 ...

Single-nucleotide polymorphism microarray analysis identifies copy-number variants and blocks of homozygosity, suggestive of consanguinity or uniparental disomy. The purpose of this study was to ...

The causes of PS are unknown, but it has been hypothesized that the syndrome is a result of somatic mutations, which are lethal in the non-mosaic state. 8 A genome-wide scan could reveal genetic ...

SALT LAKE CITY--(BUSINESS WIRE)-- ARUP Laboratories, a leading national clinical and anatomic pathology reference laboratory and a leader in innovative laboratory research and development, is pleased ...

Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Twist Bioscience Corporation (Nasdaq: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon ...

Agilent Technologies, Inc. has announced that NIMGenetics S.L. of Madrid has achieved Certified Service Provider (CSP) status for genomic research using Agilent SurePrint comparative genomic ...

SANTA CLARA, Calif.--(BUSINESS WIRE)--Affymetrix Inc. (Nasdaq:AFFX) today announced that the Genetic Association Information Network (GAIN) will use the recently launched Genome-Wide Human SNP Array 6 ...

Microarray technology has come of age as a powerful approach to revealing the genome and its dynamic expression through the application of gene-hybridization or gene-expression microarrays. While the ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

The sequencing of the human genome afforded the development of chromosomal microarrays that can be used to detect gains and losses of the genome. Microarrays are constructed from large pieces of ...