Objective: To study the demographic characteristics of patients with carpal tunnel syndrome and changes in incidence over time. Methods: Prospective collection of neurophysiological and clinical data ...

Defining the syndrome The syndrome of painful ophthalmoplegia consists of periorbital or hemicranial pain, combined with ipsilateral ocular motor nerve palsies, oculosympathetic paralysis, and sensory ...

Objective: To evaluate the relation between lesions of various brain structures and the development of eating disorders and thus inform the neurobiological research on the aetiology of these mental ...

Background The advent of immune checkpoint inhibitor therapy(iCP) has revolutionised treatment for malignant melanoma and other malignancies. Hypophysitis with resulting central hypoadrenalism is a ...

Background: The 39 item Parkinson’s disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson’s disease. However, several fundamental measurement assumptions ...

Background Neuropsychiatric symptoms (NPS) occur in nearly all Huntington’s Disease (HD) patients during the disease course. Irritability is a common NPS and is often the first sign of the disease.

Alzheimer’s disease is one of the most common causes of mental deterioration in elderly people, accounting for around 50%-60% of the overall cases of dementia among persons over 65 years of age. The ...

OBJECTIVE To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change. METHODS An informant based semistructured behavioural interview, ...

Objectives: Hepatitis C virus (HCV) infection is often associated with cryoglobulinaemia (CG). Peripheral neuropathy (PN) is a comparatively common complication of CG associated with HCV infection and ...

Background The diagnosis of dementia with Lewy bodies (DLB) is based on diagnostic clinical criteria, which were updated over the years. Objective To evaluate, through a systematic review, accuracy of ...

Background We investigated the clinical characteristics and outcomes of myelin oligodendrocyte glycoprotein (MOG) antibody-associated autoimmune encephalitis (MOGAE) in adult patients. Methods From an ...

Background A GGGGCC hexanucleotide repeat expansion in C9ORF72 occurs on a chromosome 9p21 locus that is linked with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) in white ...