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BACKGROUND: Vaccine injections can cause acute pain and distress in infants, which can contribute to dissatisfaction with the vaccination experience and vaccine hesitancy. We sought to compare the ...

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...

KEY POINTS Postural orthostatic tachycardia syndrome (POTS) is a chronic multisystem disorder; the cardinal feature is orthostatic tachycardia. Patients with POTS have symptoms of orthostatic ...

Methods The Canadian Task Force on Preventive Health Care is an independent panel of clinicians and methodologists that makes recommendations about clinical manoeuvres aimed at primary and secondary ...

Despite declining fertility, women over 40 years of age require effective contraception if they wish to avoid pregnancy. According to the 2011 Canadian census, 15% of the female population was aged 40 ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Background: Ground-level falls are common among older adults and are the most frequent cause of traumatic intracranial bleeding. The aim of this study was to derive a clinical decision rule that ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It is a clinical spectrum of ...

Testosterone deficiency syndrome, also known as late-onset hypogonadism, is a clinical and biochemical syndrome that can occur in men in association with advancing age. The condition is characterized ...

Background: The implementation and clinical impact of machine learning–based early warning systems for patient deterioration in hospitals have not been well described. We sought to describe the ...

Box 1: Evidence used in this review We conducted a targeted search of Google Scholar and PubMed to identify original research, review articles and clinical practice guidelines published through ...