本研究针对老年患者使用阿哌沙班 (apixaban)时肾功能对药物代谢的影响这一临床难题，通过前瞻性观察36名≥65岁急性住院患者，首次揭示严重肾功能不全 (GFR<30 ml/min)患者需减少70%剂量才能避免出血风险。研究采用UPLC-MS/MS精准检测血清浓度，为DOACs个体化用药提供了关键循证依据。

I had a complete hysterectomy in my late 40s due to endometriosis. I am now 68 and have been on 0.1-mg patches of estradiol ...

The first patient has been treated with InterVene’s Recana thrombectomy system for restoring patency (blood flow) in chronically obstructed deep veins and venous stents.

I have low serum cholesterol but a high coronary calcium score, and I was told to take magnesium supplements to bring my ...

The BMS-Pfizer Alliance announced a new direct-to-patient option for purchasing discounted apixaban (Eliquis) beginning in ...

New meta-analysis finds oral anticoagulants reduce net adverse events in patients with atrial fibrillation after intracranial hemorrhage but with a higher risk for recurrent intracranial hemorrhage.