BACKGROUND Antenatal screening for cystic fibrosis has been endorsed by the US National Institutes of Health. Edinburgh is the only city in the UK with an established routine antenatal screening ...

A review of the history of confidential enquiries The Confidential Enquiry into Maternal and Child Health (CEMACH) was established in April 2003. It replaces CESDI (the Confidential Enquiry into ...

Aims To ascertain whether the parameters on the Sepsis Trust screening and action tool, a tool to help clinical staff recognise and treat sepsis swiftly, are useful indicators of septic children.

Objective To study the impact of body mass index (BMI) SD score (SDS) improvement through lifestyle modification on metabolic risk and body composition over 12 months. Design Prospective cohort study.

Conclusion Consumption of slush ice drinks containing glycerol may cause a clinical syndrome of glycerol intoxication in young children, characterised by decreased consciousness, hypoglycaemia, lactic ...

Background Cognitive ability and socioemotional behaviour during childhood have independently been shown to impact educational outcomes. The extent to which their co-development predicts these ...

Objective Neural tube defects (NTDs) are a preventable folate deficiency disorder; increasing folic acid intake through food fortification increases serum and red blood cell folate and reduces the ...

Premature adrenarche (PA) is characterised by early maturation of the zona reticularis of the adrenal gland before 8 and 9 years in girls and boys, respectively.1 Biochemical analysis of androgens is ...

Objective Routine varicella zoster vaccination for children aged 18 months began in Australia from November 2005. The aim of this study was to compare the current incidence and outcomes of congenital ...

Objective Horner’s syndrome (HS) is characterised by a triad of ocular miosis, ptosis and anhidrosis. HS may be a subtle sign of occult pathology in otherwise asymptomatic children, neuroblastoma (NBL ...

Background Conflict in healthcare is a well-recognised but under-examined phenomenon. Little is known about the prevalence and causes of conflict across paediatric specialties. Objective To report the ...

Objectives Sleep-disordered breathing is a key childhood complication in children with achondroplasia. This retrospective study aimed to document the prevalence of sleep-disordered breathing in ...