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TAMs 特异性 ARF1 抑制重编程胶质瘤微环境并增强溶瘤腺病毒疗效
为解决胶质瘤免疫抑制微环境致免疫治疗效果差的问题,研究人员开展 TAMs 特异性 ARF1 抑制联合溶瘤腺病毒的研究,发现其可重编程 TAMs、增强 cGas/STING 激活及抗肿瘤免疫,为胶质瘤治疗提供新策略。 在癌症治疗领域,胶质瘤因其高度恶性和复杂的免疫微环境 ...
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